Publication:
Assessment of apolipoprotien e and paraoxonase 1 192Q/R gene polymorphisms in hypertension

dc.contributor.affiliation#PLACEHOLDER_PARENT_METADATA_VALUE#en_US
dc.contributor.authorIbrahim, Wisam Nabeelen_US
dc.date.accessioned2024-10-09T04:35:54Z
dc.date.available2024-10-09T04:35:54Z
dc.date.issued2011
dc.description.abstractHypertension is a chronic cardiovascular disease that affects 43% of the Malaysian adult population. Hypertension is associated with significantly high morbidity and mortality rates. The exact cause of hypertension is still unknown but it is believed that hypertension occurs from complex interactions between multiple environmental and genetic factors. Although much is known about the environmental factors that predispose individuals to hypertension but the molecular mechanisms behind hypertension are still poorly understood. Between 30 and 60% of blood pressure variations are determined by genetic factors. A wide spectrum of genes has been studied for their possible role in the pathogenesis of hypertension, however very few genes have shown significant role in hypertension. Numerous recent studies on apoE and PON-1 proteins have shown that both proteins exhibit an anti atherosclerotic and antioxidant roles in the human body. Polymorphisms within the genes encoding these proteins have been linked with various pathologies including cardiovascular diseases, cognitive and infectious diseases. Apolipoprotein E (Apo E) is a plasma protein responsible for plasma clearance of triglyceride and cholesterol-rich lipoproteins. Theen_US
dc.description.callnumbert RC 685 H8 I14A 2011en_US
dc.description.degreelevelMasteren_US
dc.description.identifierThesis : Assessment of apolipoprotien e and paraoxonase 1 192Q/R gene polymorphisms in hypertension /by Wisam Nabeel Ibrahimen_US
dc.description.identityt00011253027WisamNabeelen_US
dc.description.kulliyahKulliyyah of Medicineen_US
dc.description.notesThesis (MMDSC)--International Islamic University Malaysia, 2011en_US
dc.description.physicaldescriptionxvi, 123 leaves : ill. ; 30cmen_US
dc.description.programmeMaster of Medical Sciencesen_US
dc.identifier.urihttps://studentrepo.iium.edu.my/handle/123456789/10736
dc.identifier.urlhttps://lib.iium.edu.my/mom/services/mom/document/getFile/UYBemboOdu74GJzB8FVV3CKd3O47Ncfc20130321085741704
dc.language.isoenen_US
dc.publisherKuantan: International Islamic University Malaysia, 2011en_US
dc.rightsCopyright International Islamic University Malaysia
dc.subject.lcshHypertensionen_US
dc.subject.lcshHypertension--Genetic aspectsen_US
dc.titleAssessment of apolipoprotien e and paraoxonase 1 192Q/R gene polymorphisms in hypertensionen_US
dc.typeMaster Thesisen_US
dspace.entity.typePublication

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