Publication:
Effects of the oil palm (Elaeis guineensis Jacq.) on lipid oxidation in streptozotocin-induced diabetic rats

dc.contributor.affiliation#PLACEHOLDER_PARENT_METADATA_VALUE#en_US
dc.contributor.authorLim, Chin Choonen_US
dc.date.accessioned2024-10-09T04:36:23Z
dc.date.available2024-10-09T04:36:23Z
dc.date.issued2008
dc.description.abstractAntioxidant properties of the phytonutrient-rich oil palm (Elaies guineensis Jacq.) were evaluated in normal and streptozotocin (STZ)-induced diabetic rats. Thirty adult male Sprague-Daley rats were divided into 4 groups: 1) untreated-control rats, 2) only palm oil (PO) (10 ml/kg body wt., orally, for 3 weeks) treated rats, 3) STZ-induced diabetic rats (65 mg/kg intraperitoneally); 4) STZ-induced diabetic rats supplemented with PO (10 ml/kg body wt.,orally) for 3 weeks prior to the STZ-induction. After one week, body weights of the STZ-induced diabetic rats decreased compared to control, whereas thiobarbituric acid reactants (TBARS) levels - an indirect measurement of lipid peroxidation product - were significantly (p=0.001) increased by diabetes but remained unaffected by PO supplement to diabetic rats. No increase in ferric reducing ability of plasma (FRAP) was observed in palm oil treated diabetic rats compared to diabetic control rats. On the contrary, the FRAP level of PO-treated rats was about 20- fold higher (p < 0.05) compared to that of untreated-control group, whilst, a slightly increase in the TBARS level of about 17% was detected in the PO-treated rats. In conclusion, the supplementation of palm oil as an antioxidant to a certain extent reduced lipid oxidation in healthy rats, but worsened or not significantly inhibited in diabetic rats.en_US
dc.description.callnumbert QP751L732E 2008en_US
dc.description.degreelevelMaster
dc.description.identifierThesis : Effects of the oil palm (Elaeis guineensis Jacq.) on lipid oxidation in streptozotocin-induced diabetic rats / by Lim Chin Choonen_US
dc.description.identityt00011026381LIMCHINCHOONQP751L732E2008en_US
dc.description.kulliyahKulliyyah of Medicineen_US
dc.description.notesThesis (MMED Sc.)--International Islamic University Malaysia, 2008en_US
dc.description.physicaldescriptionxiii, 47 leaves : ill. ; 30 cm.en_US
dc.description.programmeMaster of Medical Scienceen_US
dc.identifier.urihttps://studentrepo.iium.edu.my/handle/123456789/10795
dc.identifier.urlhttps://lib.iium.edu.my/mom/services/mom/document/getFile/sIQiJYe0UWDMJKDZ4A8HV2BzeqoMr1fX20080815111145765
dc.language.isoenen_US
dc.publisherGombak : International Islamic University Malaysia, 2008en_US
dc.rightsCopyright International Islamic University Malaysia
dc.subject.lcshLipids -- Oxidation -- Research -- Methodologyen_US
dc.subject.lcshStreptozotocin -- Testingen_US
dc.subject.lcshDiabetes -- Animal modelsen_US
dc.titleEffects of the oil palm (Elaeis guineensis Jacq.) on lipid oxidation in streptozotocin-induced diabetic ratsen_US
dc.typeMaster Thesisen_US
dspace.entity.typePublication

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